Medscape - Spasticity-specific dosing for Zanaflex (tizanidine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost. It works by calming down nerve activity in the spinal cord, which helps loosen tight, stiff muscles. People take it by mouth as a tablet or capsule, usually only when they need relief since its. Tizanidine (Zanaflex) is a muscle relaxant that treats muscle spasms. It relaxes your muscles, which reduces muscle stiffness. Zanaflex is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Zanaflex is used to treat spasticity in adults, such as that associated with diseases like multiple sclerosis and spinal cord injuries, by temporarily relaxing muscle tone. Tizanidine, sold under the brand names Zanaflex and Sirdalud among others, is an α 2 -adrenergic receptor agonist and muscle relaxant which is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. [1][3][4] Its effectiveness appears to be similar to that of other muscle relaxants like. Learn about tizanidine (Zanaflex) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Tizanidine (Zanaflex) is a prescription muscle relaxant that is not a controlled substance. Physical dependence can develop, and suddenly stopping treatment may cause withdrawal symptoms, including high blood pressure and a fast heart rate. Tizanidine is used to help relax certain muscles in your body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, including multiple sclerosis or certain injuries to the spine. Learn about Zanaflex: What is it used for, what you need to know before taking, important warnings and safety info, how to take, side effects and more. Zanaflex (Tizanidine) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources.